Shared genetic background between SARS-CoV-2 infection and large artery stroke.

Livia ParodiEvangelos Pavlos MyserlisJaeyoon ChungMarios K GeorgakisErnst MayerhoferJonathan HenryBailey E MontgomeryMandy MoyHuichun XuRainer MalikCarl D LangefeldMartin Dichgansnull nullDaniel WooJonathan RosandChristopher D Andersonnull null

Published in: International journal of stroke : official journal of the International Stroke Society (2022)

Presence of genetic correlation and significant pathway enrichment suggest that increases in LAS risk reported in COVID-19 patients may be intrinsic to the viral infection, rather than a more generalized response to severe illness.

Keyphrases

genome wide
copy number
sars cov
early onset
dna methylation
gene expression
brain injury
coronavirus disease
blood brain barrier
drug induced