Energy Transfer between Semiconducting Polymer Dots and Gold Nanoparticles in a Photoelectrochemical System: A Case Application for Cathodic Bioanalysis.
Xiao-Mei ShiLi-Ping MeiQian WangWei-Wei ZhaoJing-Juan XuHong-Yuan ChenPublished in: Analytical chemistry (2018)
We report herein the energy transfer (ET) between semiconducting polymer dots (Pdots) and gold nanoparticles (Au NPs) in a photoelectrochemical (PEC) system and its feasibility for cathodic bioanalysis application. Specifically, COOH-capped Pdots were first fabricated and then assembled onto the indium-tin oxide (ITO) surface, followed by the modification of single-strand (ss) DNA probe (pDNA). After the DNA hybridization with the Au NP-tethered complementary ssDNA (Au NP-tDNA), the Au NPs were brought into the close proximity of Pdots. Upon light stimulation, photoluminescence (PL) was annihilated, fluorescence was attenuated, and the photocurrent intensity was evidently decreased. This ET-based PEC DNA sensor exhibited a linear range from 1 fM to 10 pM with a detection limit of 0.97 fM at a signal-to-noise ratio of 3. The present work first exploited the ET between Pdots and Au NPs, and we believe this phenomenon will spark new interest in the study of various Pdots-based ET-influenced PEC systems and thus catalyze increasing studies for specific bioanalytical purposes.
Keyphrases
- energy transfer
- quantum dots
- sensitive detection
- gold nanoparticles
- reduced graphene oxide
- single molecule
- loop mediated isothermal amplification
- circulating tumor
- cell free
- visible light
- air pollution
- nucleic acid
- oxide nanoparticles
- label free
- fluorescent probe
- living cells
- molecularly imprinted
- high intensity
- risk assessment
- circulating tumor cells