Outcome for pediatric acute promyelocytic leukemia patients at Children's Oncology Group sites on the Leukemia Intergroup Study CALGB 9710 (Alliance).

Matthew A KutnySusan GeyerKristina M LaumannJohn GregoryCheryl L WillmanWendy StockRichard A LarsonBayard L PowellJames H Feusner

Published in: Pediatric blood & cancer (2018)

Our data demonstrate that intensified ATRA, cytarabine, and anthracycline chemotherapy is effective for pediatric APL including very young patients, but early deaths and relapses remain barriers to cure. Further improvements are likely with incorporation of ATO into pediatric APL regimens.

Keyphrases

acute myeloid leukemia
bone marrow
end stage renal disease
ejection fraction
newly diagnosed
young adults
prognostic factors
liver failure
high dose
squamous cell carcinoma
intensive care unit
low dose
drug induced
acute respiratory distress syndrome
machine learning
data analysis
rectal cancer