Major complications of aspirin desensitization and maintenance therapy in aspirin-exacerbated respiratory disease.
Auddie M SweisTran B LockeKevin I Ig-IzevbekhaiTheodore C LinPatrick K GleesonAlyssa M CivantosAnkur KumarAndrew M CorrMichael A KohanskiJames N PalmerJohn V BossoNithin D AdappaPublished in: International forum of allergy & rhinology (2020)
AD with ATAD was associated with only a 0.92% incidence of a clinically significant GI bleed, and only a 0.92% incidence of anaphylaxis. A remaining 16 patients (14.7%) discontinued aspirin therapy due to minor clinical sequelae. These findings demonstrate that the majority of AERD patients tolerate AD with ATAD without any major complications.