Peripheral blood BRCA1 methylation profiling to predict familial ovarian cancer.
Yuyeon JungSoo Young HurJing Jing LiuSanha LeeByung Soo KangMyung-Shin KimYoun Jin ChoiPublished in: Journal of gynecologic oncology (2021)
Our data suggest a predictive role of BRCA1 methylation profile for ovarian cancer in those without a history of cancer but with an FHC. BRCA1 methylation has important implications for diagnostic and predictive testing of those with BRCAwt cancer(-) status with FHC.