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Effect of different conditioning regimens on survival and engraftment for children with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoeitic stem cell transplantation: A single institution experience.

Salah AliDonna A WallMuhammad AliKuang-Yueh ChiangAhmed NaqviSheila WeitzmanAdam GassasPaul GibsonRae BragerConrad V FernandezBruce CrooksTal SchechterJoerg Krueger
Published in: Pediatric blood & cancer (2021)
The intensity of the preparative regimen has a significant impact on outcome of HSCT for HLH. The newly described treosulfan-based RTC provides for a stable graft with a reasonable toxicity profile.
Keyphrases
  • stem cell transplantation
  • high dose
  • hematopoietic stem cell
  • young adults
  • oxidative stress
  • high intensity
  • low dose
  • free survival
  • oxide nanoparticles