Prognostic significance of matrix metalloproteinase 9 in COMET operated chronic ocular Stevens-Johnson syndrome.
Renu VenugopalNamrata SharmaSeema SenSujata MohantySeema KashyapTushar AgarwalJasbir KaurRasik B VajpayeePublished in: The British journal of ophthalmology (2021)
Our findings suggest that differential expression of MMPs and TIMP1 is seen in SJS in chronic stage. Emergence of MMP9 as a poor prognostic predictor of BCVA post COMET and postoperative MMP9 immunoassay positivity could be a useful tool in further studies to understand the unresolved ocular surface inflammation seen in SJS.