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Comparing the clinical outcomes of initial surgery and primary definitive radiotherapy with a dosage of 6600 cGy or higher in cT1-2N0M0 oral cavity squamous cell carcinoma: A nationwide cohort study.

Chien-Yu LinWen-Cheng ChenYu-Wen WenKang-Hsing FanJin-Ching LinShu-Hang NgYao-Te TsaiShu-Ru LeeChung-Jan KangLi-Yu LeeChih-Yen ChienChun-Hung HuaCheng Ping WangTsung-Ming ChenShyuang-Der TerngChi-Ying TsaiHung-Ming WangJason Chia-Hsun HsiehChih-Hua YehChih-Hung LinChung-Kan TsaoNai-Ming ChengTuan-Jen FangShiang-Fu HuangLi-Ang LeeKu-Hao FangYu-Chien WangWan-Ni LinLi-Jen HsinTzu-Chen YenChih-Hung Lin
Published in: Cancer medicine (2024)
In Taiwanese patients with cT1-2N0M0 OCSCC, a remarkably low proportion (1.1%) completed definitive RT. A significant survival disparity of 30% was observed between patients who underwent initial surgery and those who received definitive RT. Interestingly, even patients from the surgical group with positive surgical margins exhibited a significantly superior survival compared to those in the definitive RT group.
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