siRNA Targeting ECE-1 Partially Reverses Pulmonary Arterial Hypertensionassociated Damage in a Monocrotaline Model.
Citlali Margarita Blancas-NapolesSandra Edith Cabrera-BecerraVivany Maydel Sierra-SánchezSergio Adrian Ocampo-OrtegaVanessa Giselle Garcia-RubioRodrigo Romero-NavaFengyang HuangEnrique HongAsdrúbal Aguilera-MéndezSantiago VillafañaPublished in: Current molecular pharmacology (2024)
Based on the above information, we conclude that the administration of siRNAs directed to ECE-1 decreases the damage associated with PAH.