Efficacy of Continuous vs. Intermittent Administration of Cefepime in Adult ICU Patients with Gram-Negative Bacilli Bacteremia: A Randomized Double-Blind Clinical Study.
Carlos Álvarez MorenoLaura Cristina Nocua-BáezGuillermo OrtizJuan Carlos TorresGabriel MontenegroWilliams CerveraLuis Fernando ZuluagaAlonso GómezPublished in: Antibiotics (Basel, Switzerland) (2024)
The results of this study support the use of cefepime for the treatment of Gram-negative infections in critically ill patients, but we could not demonstrate differences between continuous or intermittent administration because of the small sample size, given the early suspension of the study.