Relapse Timing Is Associated With Distinct Evolutionary Dynamics in Diffuse Large B-Cell Lymphoma.
Laura K HiltonHenry S NguBrett J CollingeKostiantyn DrevalSusana Ben-NeriahChristopher K RushtonJasper C H WongManuela CruzAndrew RothMerrill BoyleBarbara MeissnerGraham W SlackPedro FarinhaJeffrey W CraigAlina S GerrieCiara L FreemanDiego R VillaJudith A RodrigoKevin SongMichael CrumpLois E ShepherdAnnette E HayJohn KuruvillaKerry J SavageRobert KridelAly KarsanMarco A MarraLaurie Helen SehnChristian SteidlRyan D MorinDavid W ScottPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
These results suggest that late relapses commonly represent genetically distinct and chemotherapy-naïve disease and have implications for optimal patient management.