Systemic Lupus Erythematosus Delivery Outcomes Are Unchanged Across Three Decades.
April BarnadoJanie HubbardSarah GreenAlex CamaiLee WhelessSarah OsmundsonPublished in: ACR open rheumatology (2022)
We observed rates of preeclampsia and preterm delivery in SLE that were five times higher than the general population and higher compared with other prospective SLE cohorts. Furthermore, we did not observe improved outcomes over time with preeclampsia and preterm delivery. Despite increasing evidence for universal use of hydroxychloroquine and aspirin, we did not observe substantially higher use of these medications over time, particularly for aspirin. Our results demonstrate the continued need to prioritize educational and implementation efforts to improve adverse pregnancy outcomes in SLE.
Keyphrases
- systemic lupus erythematosus
- pregnancy outcomes
- disease activity
- low dose
- pregnant women
- early onset
- cardiovascular events
- preterm birth
- primary care
- low birth weight
- healthcare
- quality improvement
- antiplatelet therapy
- rheumatoid arthritis
- gestational age
- type diabetes
- emergency department
- percutaneous coronary intervention
- anti inflammatory drugs