Rates of, and factors associated with, switching among generic levothyroxine preparations in commercially insured American adults.

Juan P BritoYihong DengJoseph R RossNam Hee ChoiDavid J GrahamYandong QiangElena RantouZhong WangLiang ZhaoNilay D ShahKasia J Lipska

Published in: Endocrine (2022)

One in five patients switched among generic L-thyroxine manufacturers within one year of treatment initiation. Generic L-thyroxine switching occurred more often when more pharmacies were used to fill L-thyroxine. Given existing guideline recommendations, additional studies should clarify the impact of generic L-thyroxine switching on thyroid hormone values.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
patient reported outcomes
clinical practice
combination therapy
patient reported