The interaction between glycemic index, glycemic load, and the genetic variant ADIPOQ T45G (rs2241766) in the risk of colorectal cancer: a case-control study in a Korean population.

Y-Thanh LuMadhawa GunathilakeJeonghee LeeJae Hwan OhHee Jin ChangDae Kyung SohnAesun ShinJeong-Seon Kim

Published in: European journal of nutrition (2022)

Overall, our study suggests positive associations of GI and GL with CRC risk. Moreover, the associations of GI and GL with rectal cancer risk could be modified by ADIPOQ T45G in a Korean population. Further studies with larger sample sizes are needed to confirm our findings.

Keyphrases

type diabetes
glycemic control
gene expression
copy number
dna methylation
insulin resistance
case control
breast cancer risk