Polyvinyl Alcohol (PVA)-Based Nanoniosome for Enhanced in vitro Delivery and Anticancer Activity of Thymol.

Mohammadreza AbdihajiMasoumeh Mirzaei ChegeniAlireza HadizadehNegar FarrokhzadZahra KheradmandParastoo FakhrfatemiFardad FaressKasra Moeinabadi-BidgoliHassan NoorbazarganEbrahim Mostafavi

Published in: International journal of nanomedicine (2023)

Overall, the results of this study revealed that Nio-TH/PVA may effectively transport hydrophobic drugs to cancer cells with a controlled-release profile to induce apoptosis while exhibiting no detectable side effects due to their biocompatibility with normal cells.

Keyphrases

cell cycle arrest
induced apoptosis
endoplasmic reticulum stress
cell death
oxidative stress
pi k akt
single cell
signaling pathway