MicroRNA-299-3p inhibits cell proliferation, motility, invasion and angiogenesis via VEGFA in upper tract urothelial carcinoma.

Chien-Shen WangYi-Chen LeeJhen-Hao JhanWei-Ming LiLin-Li ChangA-Mei HuangHui-Hui LinYi-Ru WuWei-Chi HsuHung-Lung Ke

Published in: The journal of gene medicine (2023)

Our findings suggest that miR-299-3p possibly suppresses UTUC cell proliferation, motility, invasion and angiogenesis via VEGFA. VEGFA may act as a prognostic predictor, and both VEGFA and miR-299-3p could be potential therapeutic targets for UTUC.

Keyphrases

cell proliferation
endothelial cells
cell migration
vascular endothelial growth factor
biofilm formation
cell cycle
signaling pathway
pi k akt
wound healing
pseudomonas aeruginosa
candida albicans