Obesity influences the proteome of periodontal ligament tissues following periodontitis induction in rats.

Maria Eduarda Scordamaia Lopes Camila Chiérici Marcantonio Rafael Scaf de Molon Paulo Sergio Cerri Cristiane Ribeiro Salmon Luciana Souto Mofatto Francisco Humberto Nociti JuniorJames DeschnerJoni Augusto Cirelli Andressa Vilas Boas Nogueira

Published in: Journal of periodontal research (2022)

Histologically, it was found that obesity did not significantly affect bone loss resulting from periodontitis. However, the present study's findings indicated that obesity affects the proteome of PDL submitted to experimental periodontitis, allowing for identifying potential targets for personalized approaches.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
bone loss
type diabetes
weight gain
adipose tissue
skeletal muscle
body mass index