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RAF1- rearranged Spindle Cell Mesenchymal Tumor With Calcification and Heterotopic Ossification: A Case Report and Review of Literature.

Fleur CordierSiebe LoontiensJoni Van der MeulenLore LapeireGabrielle H van RamshorstGwen SysJo Van DorpeDavid Creytens
Published in: International journal of surgical pathology (2023)
We report an exceptional case of a spindle cell mesenchymal tumor with S100 and CD34 co-reactivity, which harbored a SLMAP::RAF1 fusion. To the best of our knowledge, this is the second case of a spindle cell mesenchymal tumor with S100 and CD34 co-reactivity with this specific fusion. Remarkable is the presence of calcification and heterotopic ossification in the center of our lesion, a feature that, to our knowledge, has not been described yet in RAF1 -rearranged spindle cell mesenchymal tumors.
Keyphrases
  • single cell
  • stem cells
  • bone marrow
  • cell therapy
  • healthcare
  • chronic kidney disease
  • machine learning