Mesenchymal stem cells may ameliorate inflammation in an ex vivo model of extracorporeal membrane oxygenation.
Viktor von BahrJonathan E MillarMaximillian V MalfertheinerKatrina K KiMargaret R PassmoreNicole BartnikowskiMeredith A ReddMichael CavayeJacky Y SuenDanny F McAuleyJohn F FraserPublished in: Perfusion (2020)
The addition of mesenchymal stem cells during extracorporeal membrane oxygenation may cause an increase in transforming growth factor-β1. This is despite their ability to adhere to the membrane oxygenator. Further studies are required to confirm these findings.
Keyphrases
- extracorporeal membrane oxygenation
- mesenchymal stem cells
- transforming growth factor
- acute respiratory distress syndrome
- umbilical cord
- epithelial mesenchymal transition
- respiratory failure
- bone marrow
- oxidative stress
- cell therapy
- case control
- mechanical ventilation
- signaling pathway
- stem cells
- intensive care unit