Classifying Patients Operated for Spondylolisthesis: A K-Means Clustering Analysis of Clinical Presentation Phenotypes.
Andrew K ChanThomas A WoznyErica F BissonBrenton H PennicookeMohamad BydonSteven D GlassmanKevin T FoleyChristopher I ShaffreyEric A PottsMark E ShaffreyDomagoj CoricJohn J KnightlyPaul ParkMichael Y WangKai-Ming FuJonathan R SlotkinAnthony L AsherMichael S VirkPanagiotis KerezoudisMohammed A AlviJian GuanRegis W HaidPraveen V MummaneniPublished in: Neurosurgery (2022)
We define 2 distinct phenotypes-those with high vs intermediate disease burden-operated for lumbar spondylolisthesis. Those with high disease burden were less satisfied, had a lower quality of life, and more disability, more back pain, and more leg pain than those with intermediate disease burden, but had greater magnitudes of improvement in disability, back pain, quality of life, and more often reached ODI MCID.