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UNC13A variant rs12608932 is associated with increased risk of amyotrophic lateral sclerosis and reduced patient survival: a meta-analysis.

Baiyuan YangHaixia JiangFang WangShimei LiChongmin WuJianjian BaoYongyun ZhuZhong XuBin LiuHui RenXinglong Yang
Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2019)
The present meta-analysis suggests that rs12608932(C) is associated with increased ALS susceptibility, especially in Caucasian and European subjects, and that the CC genotype of rs12608932 is associated with reduced ALS patient survival.
Keyphrases
  • amyotrophic lateral sclerosis
  • systematic review
  • case report
  • free survival