Metastatic adult-type non-rhabdomyosarcoma soft tissue sarcomas in children and adolescents: A cohort study from the European paediatric Soft tissue sarcoma Study Group.
Andrea C FerrariDaniel OrbachMichela CasanovaMax M van NoeselPablo BerlangaBernadette BrennanNadege CorradiniReineke A SchootGema L Ramirez-VillarLisa Lyngsie HjalgrimRita AlaggioGabriela Guillen BurriezaAkmal SafwatAlison L CameronRick R van RijnVeronique Minard ColinIlaria ZanettiGianni BisognoJulia C ChisholmJohannes H M MerksPublished in: Cancer (2023)
Pediatric non-rhabdomyosarcoma soft tissue sarcomas form a heterogeneous group of rare tumors. Although recent international studies have defined the standard of care for patients with localized disease, limited data are available on the clinical behavior of patients with distant metastases. This study on 61 metastatic cases treated on two prospective European protocols confirms that the chances of survival of such patients are often dismal and a standard treatment is still lacking.
Keyphrases
- soft tissue
- squamous cell carcinoma
- small cell lung cancer
- end stage renal disease
- ejection fraction
- emergency department
- healthcare
- palliative care
- newly diagnosed
- chronic kidney disease
- intensive care unit
- high grade
- lymph node
- young adults
- peritoneal dialysis
- artificial intelligence
- chronic pain
- smoking cessation
- patient reported
- childhood cancer
- case control