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Deceptively bland cutaneous angiosarcoma on the nose mimicking hemangioma-A clinicopathologic and immunohistochemical analysis.

Christina MitteldorfMar Llamas VelascoHans-Joachim SchulzeKai-Martin ThomsThomas MentzelMichael TronnierHeinz Kutzner
Published in: Journal of cutaneous pathology (2018)
Cutaneous ASs can be rather bland and may easily be mistaken for benign vascular tumors. Both cases presented a uniform clinical picture, which implied a malignant vascular tumor. In contrast, the cytomorphology of the endothelial cells and the immunohistochemical profile were not suspicious. We worked out subtle histological criteria, which should allow an early detection of such tumors.
Keyphrases
  • endothelial cells
  • magnetic resonance
  • computed tomography
  • vascular endothelial growth factor