Glutamate and GABA neurotransmission are increased in paraventricular nucleus of hypothalamus in rats induced to 6-OHDA parkinsonism: Involvement of nNOS.

Eric Diego Turossi AmorimLorena de JagerAndressa Busetti MartinsAnanda Totti RodriguesBruno Fernando Cruz LucchettiDeborah ArizaPhileno Pinge-FilhoCarlos Cesar CrestaniErnane Torres UchoaMarli Cardoso Martins-Pinge

Published in: Acta physiologica (Oxford, England) (2019)

Our data suggest that the decreased baseline blood pressure and heart rate in animals with Parkinsonism may be due to an increased GABAergic tone via nNOS in the PVN.

Keyphrases

heart rate
blood pressure
drug induced
heart rate variability
parkinson disease
nitric oxide synthase
high glucose
hypertensive patients
electronic health record
nitric oxide
big data
deep brain stimulation
type diabetes
endothelial cells
skeletal muscle
weight loss