The Functionalized Heterogeneous Catalyst From Atomically Precise Pd 1 Au 8 Cluster Facilitates the Carbon-carbon Bond Construction.

Atomically precise metal clusters have become possible to establish a connection between homogeneous and heterogeneous catalysis. Due to their defined coordination geometry, herein we exploit atomically precise Pd 1 Au 8 (PPh 3 ) 8 2+ cluster to identify the crucial factor that can impact the catalytic efficiency for Suzuki-Miyaura cross-coupling process and further gain valuable insight into exclusively cooperative effect of the central Pd atom and the peripheral Au atoms of the Pd 1 Au 8 (PPh 3 ) 8 2+ cluster on controlling the cross-coupling reaction. Specifically, we design a heterogeneous catalyst, namely Pd 1 Au 8 @Resin by exchanging positively charged Pd 1 Au 8 (PPh 3 ) 8 2+ cluster into the porous resin, thereby not only facilitating the catalyst recyclability performed in the batch reactor but also realizing the time-on-stream performance for the Suzuki-Miyaura cross-coupling reaction carried out in the fixed-bed reactor. The integrated advantages of homogeneous complexes and heterogeneous catalysts are expected to advance the usability of atomically precise metal clusters as heterogeneous catalysts for important bond constructions in homogeneous systems. This article is protected by copyright. All rights reserved.