Platelet Mediated Inflammation in Coronary Artery Disease with Type 2 Diabetes Patients.
Ebin JohnyPathoori BhaskarMd Jahangir AlamIndra KuladhipatiRupam DasRamu AdelaPublished in: Journal of inflammation research (2021)
Our data suggests that T2DM, CAD and T2DM_CAD are associated with altered immune cell populations. Furthermore, it has been confirmed that hyperglycemia induces platelet activation and forms platelet-immune cell aggregation which may lead to the release of inflammatory cytokines and chemokines and contribute to the complexity of CAD and type 2 diabetes.
Keyphrases
- coronary artery disease
- type diabetes
- percutaneous coronary intervention
- end stage renal disease
- cardiovascular events
- coronary artery bypass grafting
- ejection fraction
- glycemic control
- newly diagnosed
- oxidative stress
- peritoneal dialysis
- prognostic factors
- electronic health record
- aortic stenosis
- acute coronary syndrome
- adipose tissue
- big data
- machine learning
- transcatheter aortic valve replacement
- patient reported outcomes
- aortic valve
- data analysis