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Assessment of the efficacy of firocoxib (Previcox®) and grapiprant (Galliprant®) in an induced model of acute arthritis in dogs.

Andrea García de Salazar AlcaláLucile GiodaAlia DehmanFrédéric Beugnet
Published in: BMC veterinary research (2019)
Firocoxib treatment prior to induction of arthritis in dogs resulted in a high level of analgesia from the first post-treatment assessment at 1.5 h through 24 h post-treatment. The reduction in lameness provided by firocoxib was consistently superior to that provided by grapiprant, which was not significantly different from untreated controls.
Keyphrases
  • rheumatoid arthritis
  • oxidative stress
  • combination therapy
  • endothelial cells
  • high glucose
  • diabetic rats
  • respiratory failure
  • stress induced