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Size and Location of Preterm Brain Injury and Associations With Neurodevelopmental Outcomes.

Thiviya SelvanathanTing GuoSteven UfkesVann ChauHelen BransonAnne R SynnesLinh G LyEdmond N Kelly DchRuth Eckstein GrunauSteven P Miller
Published in: Neurology (2024)
We found that brain injury volume and location were significant predictors of motor, but not cognitive outcomes, suggesting that different pathways may mediate outcomes across domains of neurodevelopment in preterm infants. Specifically, assessing lesion size and location may allow for more accurate identification of infants with brain injury at highest risk of poorer motor outcomes. These data also highlight the importance of socioeconomic status in cognitive outcomes, even in preterm infants with brain injury.
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