Predictors of Significant Histological Hepatic Abnormality in Treatment-Naive Patients Infected with HBeAg-Negative Chronic Hepatitis B.
Gülşah TunçerCeyda Geyiktepe-GüçlüOsman Faruk BayramlarBurcu Atasoy BozanÇiğdem YücelSerkan SürmeBetul CopurKadir Gorkem GucluKhalis MustafayevTurkan IkizceliEsen Gul UzunerMustafa YıldırımGonul SengozFiliz PehlivanogluPublished in: Infectious diseases & clinical microbiology (2024)
In our study, age, male gender, ALT, AST, HBV-DNA, LDL cholesterol, platelet count, and FIB-4 score were independent predictors of SHA in HBeAg-negative chronic hepatitis B. The most sensitive parameters for SHA were LDL and ALT. The most specific parameters were age, AST, and APRI score. SHA may occur in patients with high HBV-DNA levels, even if ALT values are normal in HBeAg-negative patients.