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Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition.

Toshio SuzukiYuji TadaSanthi GladsonRintaro NishimuraIwao ShimomuraSatoshi KarasawaKoichiro TatsumiJames West
Published in: Respiratory research (2017)
Inhibiting DPP-4 signaling by vildagliptin could ameliorate pulmonary fibrosis by downregulating EndMT in systemic LPS-induced lung injury.
Keyphrases
  • pulmonary fibrosis
  • lipopolysaccharide induced
  • inflammatory response
  • lps induced
  • signaling pathway
  • stem cells
  • bone marrow
  • endothelial cells
  • mouse model