Ca2+ -independent and voltage-dependent exocytosis in mouse chromaffin cells.

José Moya-DíazLucas BayonésMauricio MontenegroAna M CárdenasHenner KochAtsushi DoiFernando D Marengo

Published in: Acta physiologica (Oxford, England) (2019)

We demonstrated that Ca2+ -independent and voltage-dependent exocytosis is present in chromaffin cells. This process is tightly coupled to membrane depolarization, and is able to support secretion during action potentials at low basal rates. P/Q-type Ca2+ channels can operate as voltage sensors of this process.

Keyphrases

induced apoptosis
cell cycle arrest
cell death
signaling pathway
endoplasmic reticulum stress
protein kinase
oxidative stress
pi k akt