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Exosome Isolation and Detection: From Microfluidic Chips to Nanoplasmonic Biosensor.

Jianing ShenZhengtai MaJiaqi XuTianhao XueXiaoqing LvGuixian ZhuBeiju Huang
Published in: ACS applied materials & interfaces (2024)
Exosomes are becoming more widely acknowledged as significant circulating indicators for the prognosis and diagnosis of cancer. Circulating exosomes are essential to the development and spread of cancer, according to a growing body of research. Using existing technology, characterizing exosomes is quite difficult. Therefore, a direct, sensitive, and targeted approach to exosome detection will aid in illness diagnosis and prognosis. The review discusses the new strategies for exosome isolation and detection technologies from microfluidic chips to nanoplasmonic biosensors, analyzing the advantages and limitations of these new technologies. This review serves researchers to better understand exosome isolation and detection methods and to help develop better exosome isolating and detecting devices for clinical applications.
Keyphrases
  • label free
  • loop mediated isothermal amplification
  • mesenchymal stem cells
  • stem cells
  • papillary thyroid
  • real time pcr
  • high throughput
  • gold nanoparticles
  • sensitive detection
  • bone marrow
  • childhood cancer