Evaluation of the Neuroprotective Effect of Pycnogenol in a Hypoxic-Ischemic Brain Injury Model in Newborn Rats.

Ruya Çolak Aslı Celik Ayşe Gülden Diniz Senem Alkan Özdemir Osman Yılmaz Sebnem Calkavur

Published in: American journal of perinatology (2021)

· This is the first study that investigates the role of PYC in the HI brain injury model.. · PYC may be a protective agent against hypoxic-ischemic encephalopathy.. · Sevoflurane should not be preferred in rat studies where neuronal apoptosis will be investigated..

Keyphrases

brain injury
cerebral ischemia
subarachnoid hemorrhage
oxidative stress
endoplasmic reticulum stress
cell death
early onset
blood brain barrier
atomic force microscopy
cell proliferation
mass spectrometry
case control
single molecule