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Inhibiting NF-κB inducing kinase improved the motor performance of ALS animal model.

Mengjie CaoLe YiYuyan XuYunyun TianZhongyao LiYue BiMoran GuoYuanyuan LiYakun LiuXiangyang XuJiaquan SunChunyan LiWeisong Duan
Published in: Brain research (2024)
TBK1 deletion and mutant SOD1 shared the common pathological feature possibly via effects on NIK activation and inhibitor of NIK could be a novel strategy for treating ALS.
Keyphrases
  • amyotrophic lateral sclerosis
  • signaling pathway
  • machine learning
  • lps induced
  • pi k akt
  • oxidative stress
  • protein kinase
  • tyrosine kinase
  • nuclear factor
  • wild type
  • immune response
  • cell proliferation