Login / Signup

Comparison of the Effects of Mesenchymal Stem Cells with Their Extracellular Vesicles on the Treatment of Kidney Damage Induced by Chronic Renal Artery Stenosis.

Crysthiane Saveriano Rubiao Andre IshiyMilene Subtil OrmanjiEdgar MaquigussaRosemara Silva RibeiroAntonio da Silva NovaesMirian Aparecida Boim
Published in: Stem cells international (2020)
The results of this study demonstrated that the EVs released by ASCs produced beneficial results but with lower efficacy than whole cells. ASCs produced stronger effects in this model of renal chronic hypoxia, and the use of EVs instead of whole cells should be evaluated depending on the parameter to be corrected.
Keyphrases
  • induced apoptosis
  • mesenchymal stem cells
  • cell cycle arrest
  • endoplasmic reticulum stress
  • signaling pathway
  • cell death
  • bone marrow
  • cell proliferation
  • drug induced
  • combination therapy