Could hemophagocytic lymphohistiocytosis be the core issue of severe COVID-19 cases?
Violetta Opoka-WiniarskaEwelina GrywalskaJacek RolińskiPublished in: BMC medicine (2020)
The pathogenesis and clinical symptoms of severe COVID-19 indicate that an increased inflammatory response corresponding to HLH is occurring. Therefore, patients with severe COVID-19 should be screened for hyperinflammation using standard laboratory tests to identify those for whom immunosuppressive therapy may improve outcomes.