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Selective HIF stabilization alleviates hepatocellular steatosis and ballooning in a rodent model of 70% liver resection.

Samuele IesariIsabelle A LeclercqNicolas JoudiouMina KomutaAurélie DaumerieJérôme AmbroiseAlexandra DiliNatacha Feza-BingiDaela XhemaCaroline BouzinBernard GallezFrancesco PisaniEliano Bonaccorsi-RianiPierre Gianello
Published in: Clinical science (London, England : 1979) (2021)
Selective HIF stabilization did not result in an enhanced liver function after standard liver resection, but it induced interesting metabolic changes that are worth studying for their possible role in extended liver resections and fatty liver diseases.
Keyphrases
  • endothelial cells
  • insulin resistance
  • type diabetes
  • diabetic rats
  • high fat diet
  • skeletal muscle
  • stress induced