From identification to functional characterization of cyriotoxin-1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei.
Tânia C GonçalvesÉvelyne BenoitMichael KurzLaetitia LucarainSophie FouconnierStéphanie CombemaleLucie JaquillardBrigitte SchombertJean-Marie ChambardRachid BoukaibaGerhard HesslerAndrees BohmeLaurent BialyStéphane HourcadeRémy BéroudMichel De WaardServent DenisMichel PartisetiPublished in: British journal of pharmacology (2019)
The pharmacological profile of CyrTx-1a paves the way for further molecular engineering aimed to optimize the potential antinociceptive properties of this peptide.