Factors influencing the use of different methods of consent in a randomized acute stroke trial: The Third International Stroke Trial (IST-3).

Richard I LindleyIngrid KaneGeoff CohenPeter A G Sandercock

Published in: International journal of stroke : official journal of the International Stroke Society (2021)

Acute stroke trials requiring written informed consent would result in substantial selection bias. Flexible consent methods will ensure a broad range of patients are recruited, enabling trial results to be widely generalizable.Registration: This study's registered number is ISRCTN25765518.

Keyphrases

phase iii
study protocol
phase ii
clinical trial
end stage renal disease
newly diagnosed
atrial fibrillation
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes
cerebral ischemia