Immune drivers of HBsAg loss in HBeAg-negative CHB patients after stopping nucleotide analog and administration of Peg-IFN.

Mojahidul Islam Karan Kumar Jayesh Kumar Sevak Ankur Jindal Ashish Kumar Vyas Gayatri Ramakrishna Shyamasundaran Kottilil Manoj Kumar Sharma Shiv Kumar Sarin Nirupama Trehanpati

Published in: Hepatology communications (2023)

Stopping NA therapy induces flare in about 40% of HBeAg-negative patients. Peg-IFN therapy given to such patients causes immune restoration with HBsAg loss in one fourth of them.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
hepatitis b virus
prognostic factors
immune response
drug delivery
peritoneal dialysis