Rare additional chromosomal abnormalities in acute promyelocytic leukaemia resulting in rapidly fatal disease: report of a case.

Ahmed Maseh HaidarySarah NoorSahar NoorMaryam AhmadAhmad Walid YousufzaiRamin SaadaatZeeshan Ansar AhmedAbdul Jamil RasooliAhmad Shekib ZahierHaider Ali MalakzaiAbdul Sami IbrahimkhilSamuel SharifMohammad Sarwar AnwariAbdul Hadi SaqibTawab BaryaliNajla Nasir

Published in: EJHaem (2021)

Our patient presented with a rare cytogenetic profile and rapidly progressive disease. According to our extensive literature search, this was the first case of acute promyelocytic leukaemia having pathognomonic t(15;17) along with trisomy 8 and 9q deletion.

Keyphrases

liver failure
respiratory failure
multiple sclerosis
drug induced
systematic review
aortic dissection
case report
gene expression
hepatitis b virus
copy number
intensive care unit
extracorporeal membrane oxygenation
acute respiratory distress syndrome
mechanical ventilation