Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management.
George A KomnosGeorgios ChalatsisVasileios D MitrousiasMichael E HantesPublished in: Microorganisms (2022)
Infection following anterior cruciate ligament (ACL) reconstruction can be one of the most debilitating complications following ACL reconstruction. Its reported incidence is around 1%. Utilization of vancomycin for presoaking the graft is considered an established method for infection prevention. The role of other agents, such as gentamycin needs further investigation. Staphylococci are the predominant causative pathogens, while particular attention should be paid to fungal infections due to their long-standing, occult process. Recent data demonstrate that hamstrings autograft may be at an elevated risk of being contaminated leading to subsequent septic arthritis. Diagnosis is set by clinical and laboratory findings and is usually confirmed by intraoperative cultures. Treatment varies, mainly depending on the intraoperative assessment. Satisfactory outcomes have been reported with both graft retaining and removal, and the decision is made upon the arthroscopic appearance of the graft and the characteristics of the infection. Of note, early management seems to lead to superior results, while persistent infection should be managed with graft removal in an attempt to protect the articular cartilage and the knee function.
Keyphrases
- anterior cruciate ligament reconstruction
- patients undergoing
- adipose tissue
- metabolic syndrome
- machine learning
- total knee arthroplasty
- knee osteoarthritis
- risk assessment
- staphylococcus aureus
- antimicrobial resistance
- combination therapy
- insulin resistance
- decision making
- methicillin resistant staphylococcus aureus
- gram negative
- weight loss