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Selective DNA-PK inhibition enhances chemotherapy and ionizing radiation activity in soft-tissue sarcomas.

Audrey Laroche-ClaryCoralie JosensiMarie-Alix DerieppeSarah BelhommeVéronique VendrelyRaul E PerretElaine B CadoganAntoine Italiano
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
DNA-PK inhibition deserves clinical investigation to improve response to current therapies in patients with sarcoma.
Keyphrases
  • circulating tumor
  • soft tissue
  • cell free
  • single molecule
  • high grade
  • nucleic acid
  • locally advanced
  • squamous cell carcinoma
  • radiation therapy
  • rectal cancer