A dual-signal optical sensing platform of CDs-MnO 2 NS composites for facile detection of ascorbic acid based on a combination of Tyndall effect scattering and fluorescence.
ShuJing ZhouJing WanJian-Mei ZouYulan ZhangHuijun HeWei LiJiale HuJinfang NieYali YuanYun ZhangPublished in: RSC advances (2024)
A dual-signal optical sensing platform was successfully developed for the determination of ascorbic acid (AA) based on blue fluorescent carbon dots (CDs) and manganese dioxide nanosheets (MnO 2 NSs) with strong Tyndall effect (TE) scattering and fluorescence quenching capabilities. In this nanosystem, CDs-MnO 2 NS composites were employed as probes to evaluate the AA concentration. Owing to the strong reduction, the presence of the target AA could reduce the MnO 2 NSs to Mn 2+ and induce the degradation of the MnO 2 NSs, resulting in a significant decrease in the TE scattering intensity of the MnO 2 NSs and the fluorescence recovery of the CDs. Therefore, a novel optical sensor based on TE scattering and fluorescence dual detectors was developed for the sensitive determination of AA. Under optimized conditions, the limits of detection (LODs) of the two modes were 113 and 3 nM, respectively. Furthermore, the dual-signal optical sensing platform was successfully applied for the detection of AA in human serum.
Keyphrases
- quantum dots
- energy transfer
- visible light
- single molecule
- sensitive detection
- high resolution
- loop mediated isothermal amplification
- high speed
- reduced graphene oxide
- high throughput
- real time pcr
- dengue virus
- living cells
- photodynamic therapy
- gold nanoparticles
- mass spectrometry
- highly efficient
- monte carlo
- aqueous solution
- light emitting