Moderate weight change following diabetes diagnosis and 10 year incidence of cardiovascular disease and mortality.
Jean StrelitzAmy L AhernGráinne H LongMatthew J L HareGreg IrvingClare E BoothbyNicholas J WarehamSimon J GriffinPublished in: Diabetologia (2019)
Among adults with screen-detected diabetes, loss of ≥5% body weight during the year after diagnosis was associated with a lower hazard of CVD events compared with maintaining weight. These results support the hypothesis that moderate weight loss may yield substantial long-term CVD reduction, and may be an achievable target outside of specialist-led behavioural treatment programmes.
Keyphrases
- body weight
- cardiovascular disease
- weight loss
- type diabetes
- glycemic control
- bariatric surgery
- cardiovascular events
- high intensity
- risk factors
- roux en y gastric bypass
- body mass index
- gastric bypass
- weight gain
- palliative care
- physical activity
- high throughput
- obese patients
- insulin resistance
- combination therapy
- adipose tissue
- replacement therapy