Extracellular vesicles from triple-negative breast cancer cells promote proliferation and drug resistance in non-tumorigenic breast cells.
Patricia Midori Murobushi OzawaFaris AlkhilaiwiIglenir João CavalliDanielle MalheirosEnilze Maria de Souza Fonseca RibeiroLuciane Regina CavalliPublished in: Breast cancer research and treatment (2018)
EVs isolated from the HCC1806 TNBC cells are capable of inducing proliferation and drug resistance on the non-tumorigenic MCF10A breast cells, potentially mediated by changes in genes and miRNAs expression associated with cell proliferation, apoptosis, invasion, and migration.