Hypoxia regulate developmental coronary angiogenesis potentially through VEGFR2- and SOX17-mediated signaling.

Halie E VitaliBryce KuschelChhiring SherpaBrendan W JonesNisha JacobSyeda A MadihaSam ElliottEddie DziennikLily KreunCora ConatserBhupal P BhetwalBikram Sharma

Published in: bioRxiv : the preprint server for biology (2023)

Collectively, our data provide strong phenotypic evidence to show that hypoxia might regulate coronary growth in the developing mouse heart potentially through VEGF-R2- and SOX17-mediated downstream signaling pathways.

Keyphrases

endothelial cells
vascular endothelial growth factor
coronary artery disease
coronary artery
transcription factor
stem cells
signaling pathway
heart failure
electronic health record
atrial fibrillation
big data
aortic stenosis
artificial intelligence
induced apoptosis