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Recombinant soluble thrombomodulin accelerates epithelial stem cell proliferation in mouse intestinal organoids and promotes the mucosal healing in colitis.

Arong GaowaEun Jeong ParkEiji KawamotoYan QinMotomu Shimaoka
Published in: Journal of gastroenterology and hepatology (2021)
The rsTM promotes intestinal stem cell proliferation in intestinal organoids and enhances the mucosal healing during recovery phase in DSS-induced colitis.
Keyphrases
  • cell proliferation
  • ulcerative colitis
  • cell cycle
  • pi k akt
  • induced pluripotent stem cells