Development and evaluation of a droplet digital PCR assay for the diagnosis of paucibacillary leprosy in skin biopsy specimens.

Xiujun ChengLele SunQing ZhaoZihao MiGongqi YuZhenzhen WangYonghu SunChuan WangChunhua ManFanghui FuHong LiuFuren Zhang

Published in: PLoS neglected tropical diseases (2019)

We developed and evaluated a duplex ddPCR assay for leprosy diagnosis in skin biopsy samples from leprosy patients. While still costly, ddPCR might be a promising diagnostic tool for detection of PB leprosy.

Keyphrases

high throughput
end stage renal disease
fine needle aspiration
ejection fraction
ultrasound guided
chronic kidney disease
newly diagnosed
soft tissue
prognostic factors
wound healing
peritoneal dialysis