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Confound-leakage: confound removal in machine learning leads to leakage.

Sami HamdanBradley C LoveGeorg G von PolierSusanne WeisHolger SchwenderSimon B EickhoffKaustubh R Patil
Published in: GigaScience (2023)
Mishandling or even amplifying confounding effects when building ML models due to confound-leakage, as shown, can lead to untrustworthy, biased, and unfair predictions. Our expose of the confound-leakage pitfall and provided guidelines for dealing with it can help create more robust and trustworthy ML models.
Keyphrases
  • machine learning
  • artificial intelligence
  • clinical practice